Wrinkles are a natural result of aging. They are folds of the skin and can be generally categorized in two types – lines and deep wrinkles. They are most often formed in the zones most exposed to sunlight – face, neck, decollete, hands. Some other factors can trigger the appearance of more obvious wrinkles earlier: smoking, air pollution, diet, alcohol, stress. Natural facial expressions also cause wrinkles – deep horizontal lines of the forehead, vertical folds between the eyebrows and “crow’s feet” lines around the eyes. Genes are also important for the formation of wrinkles – at around the age of 30, the hereditary wrinkles and lines start appearing for most patient, because the collagen and elastin synthesis (proteins responsible for the strength and flexibility of the skin) slows down with age, as well as the speed of cell division. After 40, facial muscles start becoming weaker, and so does the power with which they hold the skin, causing looser skin and the appearance of lines. Skin also becomes thinner, and the zones around the chine lose fat, causing the formation of deeper wrinkles on the sides of the chin.