Botox - the magic of aesthetic medicine

Erases the tired look and restores the youthful radiance

Botulinum toxin (Botox) injection is the most commonly performed aesthetic procedure in the world, revolutionizing aesthetic medicine alongside hyaluronic fillers and other injectable procedures. The skillful combination of Botox with other aesthetic procedures is the modern adequate counteraction to the aging process and the preservation of a youthful appearance without surgical intervention. Treatments are able to erase a tired appearance and restore a youthful glow and natural facial oval.

Ботокс зони на приложение

What is botox

Botox is a trademark of Allergan, used throughout the world as a moniker for botulinum toxin for medical purposes. Botulinum toxin is a neurotoxic protein produced by the bacterium Clostridium botulinum. Injected into the muscles it causes a mild form of paralysis. This discovery was registered in 1897 and in 1992 the first publications appeared on its use for aesthetic purposes. Botox blocks the transmission of nerve impulses from neurons to muscle fibres. Thus, the injected muscle remains in a permanent state of relaxation for a period of 3 to 6 months or more.

Applications of Botox in aesthetic medicine

In aesthetic medicine, botox is most commonly used to temporarily smooth mimic wrinkles caused by the contraction of facial muscles in the forehead, eye and nose areas. Depending on the amount injected, muscle movement may be reduced to varying degrees or blocked completely.

The effect of the injection is temporary and completely wears off after 3 to 6 months or more. In addition to smoothing mimic wrinkles, the procedure finds application in many aesthetic corrections or treatment of medical conditions.

Botox for expression lines

Ботокс в челото

The movement of facial muscles causes folds in the facial skin, called mimic wrinkles, which if left untreated become permanent after a certain age. Botox to relax expression lines is most commonly used in the upper third of the face – horizontal forehead wrinkles, glabellar wrinkles (between the eyebrows), crow’s feet wrinkles (around the eyes) and bunny lines (wrinkles at the top of the nose). Besides the upper third of the face, botox is used to relax mimic wrinkles above the upper lip, at the corners of the mouth, neck, etc.

Botox for glabellar wrinkles

ботокс между вежди

Botox injection into the glabella (the crease between the eyebrows) is one of the most popular aesthetic procedures. It aims to relax the facial muscles that lift or furrow the brow. The effect is pronounced and depending on the amount injected, the mimic wrinkles in the forehead area can be softened or completely eliminated. The injection into the glabella, in addition to reducing or completely eliminating the mimic wrinkles, also acts preventively or smooths the already formed static wrinkles.

Crow feet botox

Бръчки пачи крак с ботокс

When we smile, a network of wrinkles forms around our eyes, which is often called “crow’s feet wrinkles”. Injecting botox into the area around the eyes relaxes the muscles that are “to blame” for the formation of these wrinkles.

Bunny lines botox

Bunny lines ботокс

Bunny lines botox aims to relax the muscles that cause the wrinkling in the upper part of the nose at the corresponding facial expression.

Gummy smile botox

Gummy smile ботокс

In some people, smiling reveals a large part of the gums, which can be a cause for embarrassment or insecurity. This is a common clinical condition that can be caused by hyper function of the upper lip muscle, excessive growth of the upper jaw, excessive growth of the front teeth, or a combination of the above factors. Injecting botox into the area, reduces the upper lip lift when smiling and mitigates or eliminates the problem completely.

Nefertiti botox

The name of this procedure comes from the Egyptian queen Nefertiti, who had a long neck and a prominent jaw. The injection in the neck area aims to achieve a younger and firmer appearance by eliminating the problem of wrinkles and sagging of the neck. Nefertiti botox is applied to the muscles in the neck and along the jawline. After the procedure applied in these two areas, the loose skin on the neck tightens and the face has a much more vibrant and smooth appearance. Nefertiti botox application is also used to restructure the chin and minimize neck lines.

Baby botox

Baby botox is an injection of a low concentration product with the mesotherapy technique. The procedure is designed to relax the facial skin overall and smooth fine lines and wrinkles without blocking the movement of facial muscles.

Other botox applications

Botox in masseter

By injecting botox into the masseter, a reduction in muscle volume is also achieved in women with a square-shaped chin in order to alter the facial oval. Thanks to the reduction of the masseter, a square or round face shape can be transformed into a triangular, oval or heart-shaped one without surgical intervention.

Botox for bruxism

Botox injection into the masseter (jaw muscles) is used to treat involuntary clenching or grinding of the teeth (bruxism) or treat deformities in the lower face. Some people unconsciously grind their teeth while awake or asleep. This pathological condition is called bruxism and causes physical pain and serious dental problems. As a consequence of bruxism, tooth enamel may be lost and tooth sensitivity may increase. At the same time, involuntary teeth grinding causes headaches, facial and ear pain. Botox application is a very effective method in the treatment of bruxism.

Botox for chronic migraine

Botox injection in the head and neck area reduces the frequency and duration of chronic migraine headache attacks. It acts as a barrier to chemicals called neurotransmitters that carry pain signals from the brain. It stops the chemicals before they reach the nerve endings around the head and neck.

Botox is also used to treat other conditions such as hemifacial spasm, cervical dystonia, cerebral palsy, bladder pain, lower back pain, neuropathic pain, and stroke.

Botox for hyperchidrosis

Excessive sweating in the armpit or palm area is called hyperhidrosis and is often the cause of negative emotions or reduced self-esteem in patients. Injecting botox into the sweat gland muscles is a very effective method of treating hyperhidrosis in the armpit or palm areas. The procedure stops sweating in the treated areas for a period of 6 to 12 months, after which it can be repeated.

During botox procedure

Botox is injected with very thin and short needles, the same as those for insulin. The procedure is short, almost painless and seems to be quite elementary from the patient’s point of view. At the same time, for your therapist this procedure requires a lot of knowledge, experience, careful advance preparation and planning. Like any other procedure at Skin Line, this one begins with an aesthetic consultation and the development of the patient’s individual treatment plan. Your therapist will familiarize you with the injection areas and the amounts of product that are needed to achieve partial or complete relaxation of the targeted muscles. Depending on the effect you wish to achieve, your therapist will calculate the total amount of botox to be used. The areas will then be cleaned, disinfected and the injection can begin.

When the effect of Botox occurs

The effect of the procedure begins to manifest itself 2-3 days after the procedure and develops over the next 10-12 days. On the 14th day after the procedure, the effect is maximally manifested, after which it slightly decreases and remains so for a period of 3 to 6 or 12 months in some cases.

Durability of Botox effect

The initial effect of botox occurs from 2 to 5 days after the procedure, and the final effect develops within 14 days. After its first placement, the relaxation period lasts about 4-6 months. During this time it is broken down by enzymes in the body and the nerve endings regain their previous function. Subsequent injection is required no earlier than 4 months after the previous procedure and ensures an extended period of action. In rare cases where botox is injected at shorter intervals it is possible that the body will develop resistance and there will be no effect from the procedure. In such cases, it is necessary to wait 6 to 8 months before the next procedure.

After Botox injection

Botox treatments aim to relax specific muscles with mathematical precision to a specific degree, according to the desired effect and the patient’s individual treatment plan. Therefore, your therapist carefully considers what amount of product to inject depending on the size and strength of the targeted muscle. It remains your responsibility to ensure that the amount injected stays exactly where it is placed to perform its task to its fullest. It is very important that you observe the following:

  • Do not go to bed until 6 hours after the procedure;
  • Do not use makeup until four hours after the injection;
  • Do not drink alcohol on the day of the procedure;
  • Avoid excessive sweating, vigorous exercise, exercise and bending over for 5 days after the procedure
  • Do not rub or massage the treated areas, or visit a sauna, steam room, or warm-up treatments in the areas of injected botox for 14 days after the procedure.

For whom Botox is an appropriate procedure

With the exception of women who are pregnant and breastfeeding and people with muscular disorders, any man or woman can benefit from botox treatments.

For whom Botox is inapplicable - contraindications

  • Hypersensitivity to the product;
  • Infections in the injection areas;
  • Blood-muscle diseases /myasthenia, etc./
  • Use of aminoglycosides, cholinesterase inhibitors, succinylcholine, calcium blockers, lincosamides, polymyxins;
  • Pregnancy or breastfeeding;
  • Inflammatory or autoimmune diseases;
  • Age over 65.
  • Allergies to certain medications or foods /eggs/;
  • Diagnosed psychiatric illness;
  • Easy bruising, bleeding, delayed wound healing, scar enlargement;

Possible side effects of botox injection

  • Most common – headache, eyelid drooping, skin flushing, skin tightness, local muscle weakness, facial pain and numbness, and nausea;
  • Others that may be related to the injection itself – bruising, redness, pain, burning, stinging and swelling;
  • In very rare cases – muscle weakness, difficulty swallowing, breathing and speech, pneumonia;

The most unpleasant side effect of botox injection in the forehead area is the so-called “eyelid drop”, when asymmetry in the opening of both eyes occurs. The problem occurs either when an inexperienced therapist injects botox too close to the muscles that lift the eyelids or when the product migrates due to failure to follow post-procedure instructions.

Botox treatments at Skin Line Aesthetic Clinics perform

Registered Botox brands in Bulgaria



Vistabel® e Botox® for sales in Europe, including Bulgaria. It is manufactured by Allergan and differs in that it comes in a pack of 50 units per vial, whereas Botox® comes in vials of 100 units.



Xeomin® is a product of Mertz Aesthetics for the European market. It differs from other botulinum toxin products in that it does not form resistance.

dysport logo


Disport® e product by Galderma Laboratories for the European market.

See prices for botulinum toxin treatments at Skin Line or buy online:

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Plovdiv, 91 Maritsa Blvd.

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Sofia, Mladost 4, Blvd. Aleksandar Malinov 91

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Sofia, 12-16 Dragan Tsankov Blvd.

Book a consultation at Skin Line Varna

Varna, 53 Knyaz Boris I Blvd.

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